The Diogenes Study, a large, multicentered, pan-European weight loss study, has attempted to determine which type of diet is best in regards to successfully maintaining weight loss. For this study, 773 adult men and women who successfully completed an 8-week weight loss phase were randomly assigned to one of five weight maintenance diets:
- Low protein (13%) + low glycemic index
- Low protein + high glycemic index
- High protein (25%) + low glycemic index
- High protein + high glycemic index
- Control diet that followed each country's dietary guidelines
- The high protein, low glycemic index diet was easier to stick to than the low protein, high glycemic index diet.
- Consumption of the low protein, high glycemic index diet resulted in a significant increase in body weight by about 3 - 4 pounds on average. Weight re-gain was not observed on average in the other diet groups.
- Diet groups high in protein, regardless of glycemic index status, re-gained 2 lbs less than diet groups low in protein.
- Use of low glycemic index diet plans, regardless of protein level, resulted in about 2 lbs less weight re-gain than diets with a high glycemic index.
- The high protein groups and the low glycemic index groups were more likely to continue losing weight compared to the low protein and high glycemic index groups. This was particularly true for the high protein, low glycemic index group.
The benefits of increasing dietary protein and decreasing the glycemic index are likely due to their effects on appetite and blood sugar metabolism. Protein has been reported to increase our feelings of fullness and help maintain that feeling longer. Foods with a low glycemic index have been shown to have little impact on blood sugar, helping us to avoid cravings and spikes in hunger. These aspects of protein and low glycemic foods might be why individuals found it easier to stay on the high protein, low glycemic index diet plan compared to the other diet plans.
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